Which boss?The seal monster or the water summon Undine?
Deathtoidiot said seal, so I'm assuming that means the monster guarding the seal. If you're dying in three hits, how did you even make it this far? You must have been avoiding every enemy. Leveling up seems like the best thing to do. And this is obvious, but make sure none of your characters have water element weapons/spells - those will heal it.Gels and LifeBottles are always useful, and put the game on Normal if it isn't. That could be the problem. Make sure you're healed before you start, and try to have your Unison Gauge full. Above all else, level up. That's the biggest thing. I learned that in Final Fantasy for NES. If your characters are even five levels above the average for where you are, everything is easier.
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